Browsing

CIViC provides a Browse section, organized into tabs, comprised of filterable tables for each of its entities: Genes, Variants, Variant Groups, Evidence, Assertions and Sources.

Each table includes columns for key fields and, where appropriate, filters and sorting controls for narrowing results to entities of interest. Results may be sorted by more than one column at a time: hold the shift key while clicking on a column header to add stack sort parameters.

Below each table a paging interface is provided to navigate through larger result sets.

Gene Table

Column

Description

Name

Gene Entrez Name

Gene Aliases

A list of additional aliases (also from Entrez)

Diseases

List of diseases associated with the Gene

Drugs

A list of drugs associated with the Gene

Variants

A count of Variants associated with the Gene

Evidence

A count of Evidence Items associated with the Gene

Assertions

A count of Assertions associated with the Gene

Variant Table

Column

Description

Variant

Name of Variant

Entrez Gene

Entrez name of associated Gene

Diseases

List of diseases associated with the Variant

Drugs

A list of drugs associated with the Variant

Evidence

A count of Evidence Items associated with the Variant

Assertions

A count of Assertions associated with the Variant

Evidence Score

CIViC’s Evidence Score for the Variant

Variant Group Table

Column

Description

Name

Name of the Variant Group

Count

Number of Variants in the Group

Genes

List of Genes associated with the Group

Evidence

A count of Evidence Items associated with the Group

Evidence Table

Column

Description

EID

Evidence ID of the Item

Gene

Gene associated with the Item

Variant

Variant associated with the Item

Description

Description of the Item

Diseases

Diseases associated with the Item

Drugs

Drugs associated with the Item

EL

Evidence Level of the Item

ET

Evidence Type of the Item

ED

Evidence Direction of the Item

CS

Clinical Significance of the Item

VO

Variant Origin of the Item

ER

Evidence Rating of the Item

Assertion Table

Column

Description

AID

Assertion ID of the Assertion

Gene

Gene associated with the Assertion

Variant

Variant associated with the Assertion

Summary

Curator’s summary of the Assertion

Diseases

Diseases associated with the Assertion

Drugs

Drugs associated with the Assertion

AT

Assertion Type

AD

Assertion Direction

AS

Clinical Significance

Evidence

Count of Evidence Items associated with the Assertion

Source Table

Column

Description

Type

Type of Source (ASCO or PubMed)

Citation ID

PubMed or ASCO ID

Authors

Authors on the Source

Year

Year of Publication or Conference

Journal

Name of Journal (PubMed) or Citation (ASCO)

Name

Title of the publication (PubMed) or abstract (ASCO)

Evidence

Count of Evidence Items associated with the Source