CIViC Knowledge Model

This section describes the details of the knowledge model that CIViC uses to organize variant interpretations, evidence, assertions and associated information about therapies, disease type, etc. Each major entity is detailed in the sections below, with each attribute of that entity detailed within its own page (roughly).

• Evidence Items
  • Evidence Overview
  • Gene
  • Molecular Profile
  • Statement
  • Evidence Level
  • Type
  • Direction
  • Significance
  • Origin
  • Disease
  • Therapy
  • Associated Phenotype
  • Source
  • Clinical Trial
  • Evidence Rating
• Assertions
  • Assertions Overview
  • Fields Shared with Evidence
  • Associated Phenotypes
  • NCCN Guideline
  • FDA Companion Test
  • Summary and Description
• Features
  • Overview of Features
  • Feature-Variant Pairs
  • Browsing Features
• Molecular Profiles
  • Molecular Profiles Overview
  • Name
  • Aliases
  • Description
  • Molecular Profile Score
• Variants
  • Variants Overview
  • Name
  • Aliases
  • My Variant Info
  • Types
  • Coordinates
  • HGVS Expressions
  • ClinVar IDs
• Genes
  • Gene Name
  • Summary
  • MyGene.info
• Fusions
  • Fusion Variants
  • Fusion Feature page
  • Fusion Variant Page
  • Fusion Variant Coordinates
• Factors
  • The Factor Page View
  • The Factor Variant Page
  • Browsing Factors
• Variant Groups
  • Summary
• Sources
  • Source Types